دانلود رایگان مقاله لاتین فعالیت کراتیناز از سایت الزویر
عنوان فارسی مقاله:
اثرات مهاری پلاسمای اتمسفری سرد بر رشد، بیوسنتز ارگوسترول، و فعالیت کراتیناز در ترایکوفایتون روبروم
عنوان انگلیسی مقاله:
Inhibitory effects of cold atmospheric plasma on the growth, ergosterol biosynthesis, and keratinase activity in Trichophyton rubrum
سال انتشار : 2016
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مقدمه انگلیسی مقاله:
1. Introduction
Dermatophytes are a group of keratinophilic fungi which contain around 40 species classified into three main genera Microsporum (skin and hair), Trichophyton (skin, hair and nail) and Epidermophyton (skin and nail). Dermatophytosis is a superficial infection in keratinized skin tissue, in nails and hair which is prevalent worldwide. In the etiology of dermatophytosis, 5 major species involved are Trichophyton rubrum, Trichophyton interdigitale, Trichophyton tonsurans, Microsporum canis, and Trichophyton violaceum [1]. They have an arsenal of proteases aimed to digest the keratin network into absorbable oligopeptides or amino acids. Dermatophytes secrete multiple serine-subtilisins and metalloendoproteases (fungalysins), formerly called keratinases, which are used for penetration into host cellular system [2e5]. The enzyme reduces disulfide bonds in keratins of skin, hair and nail. This reduction depends on a sulfite efflux pump, encoded by the TruSsu1 gene. Keratinase enzyme plays a major role in tinea diseases [6]. According to previous studies, the disease incidence is increasing every year and approximately 20%e25% of the worldpopulation is infected by dermatophytes [7,8]. The prevalence of the disease in different parts of Iran is around 2.1%e74%. Although dermatophytes are not lethal diseases, they are the most widespread among human infections. Recently development of infectious fungi is on the increase because of various reasons, such as weakening of immunity factors, overdosing antibiotics, corticosteroides and etc. Consequently, it is essential to choose skillful treatments for the inflicted patients. The common treatments contain allylamine group drugs specially, terbinafine and various azoles such as itraconazole, fluconazole and voriconazole but these have some drawbacks such as long treatment time which may affect the liver, so it is necessary to periodically monitor liver function, drugs disability to vanish fungus entirely and other side effects for instance headache, nausea, dizziness and you name it. Moreover, it has been reported that some of the strains and dermatophyte species have developed resistance to drugs and hence, there is illness recurrence [9]. Todays, scientists try to find the best way to improve the quality of treatment. Recently, the cold plasma treatment has found many applications in biomedical fields. The purpose of this research was to use a new method with high quality performance using cold atmospheric plasma (CAP) in order to treat different kinds of tinea diseases which are caused by Trichophyton rubrum. In the 1970s the first plasma was used in industrial applications. Plasma is an ionized gas which is also made of photons, electrons, positive and negative ions, atoms, free radicals and excited or non-excited molecules that are referred to as the fourth state of matter (99% of the apparent universe is in the plasma state) [10e12].
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کلمات کلیدی:
Cold atmospheric plasma inhibits the growth of ... - ScienceDirect www.sciencedirect.com/science/article/pii/S1572100015300582 by N Rahimi-Verki - 2016 - Cited by 4 - Related articles Dec 29, 2015 - Cold atmospheric plasma strongly inhibited C. albicans growth and ... Likewise, CAP strongly inhibited the ergosterol biosynthesis by the ... [PDF]Inhibitory effects of cold atmospheric plasma on the growth, ergosterol ... iranarze.ir/wp-content/uploads/2016/10/E338.pdf ergosterol biosynthesis, and keratinase activity in Trichophyton rubrum ... effect of cold atmospheric plasma (CAP) on T. rubrum growth, ergosterol biosynthesis. Inhibitory effects of cold atmospheric plasma on the growth, ergosterol ... https://www.researchgate.net/.../305415864_Inhibitory_effects_of_cold_atmospheric_pl... Inhibitory effects of cold atmospheric plasma on the growth, ergosterol biosynthesis, and keratinase activity in Trichophyton rubrum on ResearchGate, the ... Cold atmospheric plasma inhibits the growth of ... - ResearchGate https://www.researchgate.net/.../288786792_Cold_atmospheric_plasma_inhibits_the_gro... Cold atmospheric plasma inhibits the growth of Candida albicans by affecting ergosterol biosynthesis and suppresses the fungal virulence factors in vitro on ... Inhibitory effects of cold atmospheric plasma on the growth, ergosterol ... isi-dl.com/item/81653 Inhibitory effects of cold atmospheric plasma on the growth, ergosterol biosynthesis, and keratinase activity in Trichophyton rubrum. sciencedirect.com ... Cold atmospheric plasma inhibits the growth of Candida albicans by ... www.pdpdt-journal.com/article/S1572-1000(15)30058-2/abstract by N Rahimi-Verki - 2016 - Cited by 4 - Related articles Dec 28, 2015 - •Cold atmospheric plasma strongly inhibited C. albicans growth and ergosterol biosynthesis. •Cold atmospheric plasma inhibited biofilm ... PDF (1 MB) - Photodiagnosis and Photodynamic Therapy www.pdpdt-journal.com/article/S1572-1000(15)30058-2/pdf by N Rahimi-Verki - 2016 - Cited by 4 - Related articles Dec 29, 2015 - Cold atmospheric plasma inhibits the growth of Candida albicans by ... treated fungus for biofilm formation, ergosterol biosynthesis and ... References in Cold atmospheric plasma inhibits the growth of ... www.pdpdt-journal.com/article/S1572-1000(15)30058-2/references Dec 28, 2015 - Cold atmospheric plasma inhibits the growth of Candida albicans by affecting ergosterol biosynthesis and suppresses the fungal virulence ...
