دانلود رایگان مقاله لاتین عدم همکاری سلول خونساز به تشکیل استخوان از سایت الزویر
عنوان فارسی مقاله:
عدم همکاری سلولهای خونساز به تشکیل استخوان به عنوان استئوبلاست
عنوان انگلیسی مقاله:
Hematopoietic derived cells do not contribute to osteogenesis as osteoblasts
سال انتشار : 2016
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مقدمه انگلیسی مقاله:
1. Introduction
f the skeleton, is known to be induced following traumatic injury or surgery, as well as in genetic disorders such as fibrodysplasia ossificans progressiva (FOP). The process of HO is initiated by an inflammatory phase similar to bone regeneration in fracture healing while normal skeletogenesis during development does not require inflammation, suggesting that a distinct cellular mechanism is involved in HO. It has recently been demonstrated that cells playing an important role in HO differ from those in normal skeletogenesis [1]. The extensive research on the type and source of cells which give rise to osteoblasts in HO has provided a variety of candidates including circulating mesenchymal progenitor cells [2–5], Tie2-expressing cells [6] and GLAST-expressing cells [1]. Previously, we have reported that circulating bone marrow-derived osteoblast progenitor cells are recruited to bone-forming sites and give rise to osteoblasts [3]. These circulating osteoblast progenitor cells are positive for CD44 and CXCR4 and negative for CD45 [4], suggesting that they were derived from non-hematopoietic bone marrow cells. However, others have reported that circulating CD45+/Collagen I+ osteogenic precursor cells contribute to HO in patients with FOP [5], and that hematopoietic derived fibroblast-like cells, so-called fibrocytes, also have the potential to become osteoblasts [2,7,8]. Moreover, it has been reported that hematopoietic stem cells can generate functional osteoblasts [9,10]. Considering these findings and given that osteoblasts and blood cells are both embryonically derived from mesoderm, CD45+ hematopoietic derived cells might lose their CD45 expression
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کلمات کلیدی:
Hematopoietic derived cells do not contribute to osteogenesis as ... https://www.tripdatabase.com/.../9196256-Hematopoietic-derived-cells-do-not-contrib... Helping you find reliable answers | Latest evidence made easy. Osteogenesis Imperfecta: A Translational Approach to Brittle Bone ... https://books.google.com/books?isbn=0123977894 Javaid Kassim, Paul Sponseller - 2013 - Medical mesenchymal-derived cell types, this step is not necessarily predictive of in vivo bone ... cautious not to overinterpret the ability of either BMSCs or hES/ iPS-derived cells to ... The author appreciates the many contributions of his laboratory and ... Impaired osteogenesis of T1DM bone marrow-derived stromal cells ... https://stemcellres.biomedcentral.com/articles/10.1186/s13287-017-0521-6 by TM Filion - 2017 Mar 11, 2017 - Impaired osteogenesis of T1DM bone marrow-derived stromal cells ...... glucose concentration in cell culture medium does not acutely affect ... Pediatric Bone: Biology & Diseases - Page 531 - Google Books Result https://books.google.com/books?isbn=0123820405 Francis H. Glorieux, John M. Pettifor, Harald Jüppner - 2012 - Medical Cells that do populate the bone surface have markers of ... However, when bone progenitor cells (not fresh bone marrow) are implanted directly into ... a bone repair defect, donor derived bone is produced as assessed by the host and ... Upper cervical cord compression as cause of death in osteogenesis imperfecta type II. Plastic Surgery: Principles - Volume 1 - Page 239 - Google Books Result https://books.google.com/books?isbn=1455710520 Geoffrey C. Gurtner, Peter C. Neligan, Richard J. Warren - 2012 - Medical Transplantation of marrow-derived mesenchymal stem cells and platelet-rich plasma during distraction osteogenesis—a preliminary ... Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Osteoblast - Wikipedia https://en.wikipedia.org/wiki/Osteoblast Osteoblasts are cells with a single nucleus that synthesize bone. However, in the process of ... Forces that exceed the capacity of bone to behave elastically may cause .... type I cause the commonest inherited disorder of bone, called osteogenesis imperfecta. ... That is, dietary calcium does not create mineral by mass action. [PDF]Bone Marrow Stromal Cells Fail to Form Bone or Cartilage in vivo ... www.ors.org/Transactions/55/0783.pdf by Z Xing - Cited by 1 - Related articles Bone Marrow Stromal Cells Fail to Form Bone or Cartilage in vivo During Fracture ... in which the distribution of bone marrow-derived cells can be detected in vivo. ... However, these cells do not participate in chondrogenesis or osteogenesis in ...
