دانلود رایگان مقاله لاتین اسید آمینه آزاد از سایت الزویر
عنوان فارسی مقاله:
اسیدهای آمینه آزاد،محتوی کاناوانین در دانه از 32 گونه ویسیا متعلق به جنس فرعی ویسیا
عنوان انگلیسی مقاله:
Free amino acids, including canavanine, in the seeds from 32 Vicia species belonging to subgenus Vicilla
سال انتشار : 2016
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مقدمه انگلیسی مقاله:
1. Introduction
In legumes, secondary compounds include polyphenols, alkaloids, and free amino acids. Free amino acids include the 20 amino acids found in proteins, and non-protein amino acids. The latter have been traditionally considered antinutritional compounds. There are several examples of these amino acids in Vicia. Thus, β- Cyano-L-alanine is present in subgenus Vicia, including V. sativa (Megías et al., 2014), and canavanine is found in subgenus Vicilla, including V. disperma (Megías et al., 2015). Canavanine is an arginine analogue that is incorporated into proteins in plant predators, resulting in aberrant non-functional proteins (Rosenthal and Dahlman, 1991). In addition to defense from predators, canavanine has been related with drought tolerance (Enneking, 1995) and allelopathy (Nakajima et al., 2001). Despite its antinutritional properties, canavanine is also considered a functional compound since inhibits cell proliferation (Bence et al., 2002) and induces apoptosis (Jang et al., 2002). Another interesting property of canavanine is the selective inhibition of inducible nitric oxide (NO) synthase. This could limit excessive NO during inflammatory or infectious diseases, without affecting constitutive NO production (Teale and Atkinson, 1994; Abd ElGawad and Khalifa, 2001). The presence of canavanine in Vicia species belonging to subgenus Vicilla was described more than 40 years ago using thin layer chromatography (Bell and Tirimanna, 1965). We have now carried out quantification of free amino acids, including canavanine, in 32 species belonging to subgenus Vicilla, by RPHPLC. The main objective was to screen Vicia species belonging to subgenus Vicilla for new taxa that could be of interest as sources of canavanine or other free amino acids.
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کلمات کلیدی:
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