دانلود رایگان مقاله لاتین کاهش ویتامین d در زنان با عدم بارداری از سایت الزویر
عنوان فارسی مقاله:
بیان کاهش پذیرایی ویتامین D در زنان با عدم بارداری مکرر
عنوان انگلیسی مقاله:
Decreased expression of the vitamin D receptor in women with recurrent pregnancy loss
سال انتشار : 2016
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مقدمه انگلیسی مقاله:
1. Introduction
Several pathogenic mechanisms associated with recurrent pregnancy loss (RPL) have previously been described, including chromosomal anomalies, congenital uterine anomalies, acquired and inherited thrombophilia, endocrine problems, infections, autoimmune disorders, and male factors. Furthermore, up to 50% of cases of RPL have no clearly identifiable etiology [1]. Immunological mechanisms have been proposed to explain some cases of RPL. Women with RPL exhibit what is considered a generalized exaggerated inflammatory immune response during pregnancy and show signs of a disruption in the tolerance of autoantigens and fetal antigens [2]. It is well established that 1, 25 dihydroxy vitamin D3 (1,25(OH)2D3), a pleiotropic steroid hormone, has classic effects on bone metabolism and mineral homeostasis. However, the discovery that multiple functions of vitamin D3 are important for growth and development, including immune system development [3], has stimulated interest in the role that this vitamin may play during pregnancy. Several studies have suggested that vitamin D carries out important functions in a large number of immune-mediated responses [4e8]. Vitamin D3 inhibits adaptive immunity and cell proliferation and simultaneously promotes innate immunity and stimulates cellular differentiation [4]. Th17 cells, characterized by IL-17 production, play a critical role in the pathogenesis of autoimmune diseases and are inhibited by 1,25(OH)2D3 in vitro [5].
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کلمات کلیدی:
Decreased expression of the vitamin D receptor in women with ... - NCBI https://www.ncbi.nlm.nih.gov/pubmed/27477959 by X Yan - 2016 - Related articles Arch Biochem Biophys. 2016 Jul 28;606:128-133. doi: 10.1016/j.abb.2016.07.021. [Epub ahead of print]. Decreased expression of the vitamin D receptor in ... Decreased Expression of Vitamin D Receptors in ... - PLoS ONE journals.plos.org/plosone/article?id=10.1371/journal.pone.0042789 by GK Gupta - 2012 - Cited by 21 - Related articles Aug 6, 2012 - Interestingly, there was significantly decreased expression of VDR in ... Expression of VDR and TNF-α and the effect of vitamin D deficiency in ... Decreased Expression of Vitamin D Receptor Affects an Immune ... www.mdpi.com/1422-0067/18/2/289/pdf by A Kempinska-Podhorodecka - 2017 - Cited by 1 Jan 29, 2017 - www.mdpi.com/journal/ijms. Article. Decreased Expression of Vitamin D Receptor Affects an Immune Response in Primary Biliary Cholangitis. Decreased Expression of Vitamin D Receptor May Affect an Immune ... www.journal-of-hepatology.eu/article/S0168-8278(16)64005-9/abstract by AK Podhorodecka - 2016 Decreased Expression of Vitamin D Receptor May Affect an Immune Response Via VDR – MIRNA 155 - SOCS1 Pathway in Primary Biliary Cirrhosis. Decreased expression of the vitamin D receptor in women with ... https://www.researchgate.net/.../305728946_Decreased_expression_of_the_vitamin_D_r... Sep 29, 2016 - Decreased expression of the vitamin D receptor in women with recurrent pregnancy loss: on ResearchGate, the professional network for ... Vitamin D: Oxidative Stress, Immunity, and Aging https://books.google.com/books?isbn=1439850208 Adrian F. Gombart - 2012 - Medical These changes in vitamin D metabolism appear to occur before any changes in ... paradoxically, this is associated with decreased expression of VDR [39]. Endocrinology: Adult and Pediatric E-Book https://books.google.com/books?isbn=032332195X J. Larry Jameson, Leslie J. De Groot - 2015 - Medical Apart from its effects on serum calcium levels, 1,25(OH)2 D directly ... Vitamin D deficiency in animals is associated with decreased expression of CaSR mRNA ... Parathyroid Hormone Decreases Renal Vitamin D Receptor - jstor https://www.jstor.org/stable/3375117 by KD Healy - 2005 - Cited by 30 - Related articles Parathyroid hormone decreases renal vitamin D receptor expression In vivo. Kevin D. Healy, Janeen L. Vanhooke, Jean M. Prahl, and Hector F. DeLuca*. Vitamin D: Two-Volume Set - Page 785 - Google Books Result https://books.google.com/books?isbn=0123819792 David Feldman, J. Wesley Pike, John S. Adams - 2011 - Medical D. Given the scope for potential effects of vitamin D on normal pancreatic ... ovarian dysgerminomas 1a-hydroxylase expression and activity was also increased, ...
