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عنوان فارسی مقاله:
سنتز، شناسایی و اصلاح صمغ عربی میکروگلاس برای مطالعات هموسازگاری و ضد میکروبی
عنوان انگلیسی مقاله:
Synthesis, characterization and modification of Gum Arabic microgels for hemocompatibility and antimicrobial studies
سال انتشار : 2017
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مقدمه انگلیسی مقاله:
1. Introduction
Biopolymers obtained from polysaccharides are preferred for use in many biomedical applications such as high cytocompatibility and ability to degrade in body without releasing harmful substances (Ciofani et al., 2014). But still majority of biopolymers lack some essential properties like biocompatibility and mechanical stability in aqueous environments (Oh, Lee, & Park, 2009). It is of critical importance to know about the hemocompatibility and biodegradability of any material to be used in vitro and/or in vivo for biomedical applications. Various attempts such as; cross linking, breaking of the polymer chains and surface modification canbe performed to achieve relative stability and desired goals from biomaterials (de las Heras Alarcón, Pennadam, & Alexander, 2005). Natural gums are a large classification of carbohydrates with a wide range of applications especially in food, pharmaceuticals, cosmetics, adhesive, paper, textile, and other industries for centuries. The oldest and most common GA was introduced into Europe through various Arabian ports, so it was called Gum Arabic (Phillips & Williams, 2001). During the middle ages, the trade of GA was governed by the Ottoman Empire, giving rise to the name turkey gum (Verbeken, Dierckx, & Dewettinck, 2003). GA is a polydispersed molecule including a compact arabinogalactan molecule consisting of amino acids linked to short arabinose side chains (An et al., 2013). It is safe, non-digestible food element which is widely used in food and pharmaceutical industries. Positive effects linked to renal or hepatic failure are claimed by various authors (Ali, Ali, Fadlalla, & Khalid, 2008). Blocks of highly branched carbohydrates are linked to the polypeptide chain leading to a wattle blossom structure(Poologanathan & Mahendran, 2012). In soft drinks it works as an emulsifier and assists as an efficient encapsulating agent for flavor where it offers a high protection from unstable flavor compounds (Romo-Hualde, Yetano-Cunchillos, González-Ferrero, Sáiz-Abajo, & González-Navarro, 2012; Verbeken et al., 2003). GA is also used in oral or topical application due to its suspending and emulsifying nature. It is used as an ingredient in pastilles, lozenges or as a binder in tablet manufacturing (Bhardwaj, Kanwar, Lal, & Gupta, 2000). The most important application of Gum Arabic is its use as a release modifier (Malviya, Jain, & Malviya, 2010). Crosslinking of the linear chains of GA can adapt to a spherical shape enabling many applications by providing a surface which reduces degradation, is suitable for many catalytic reactions like degradation of harmful industrial effluents and reduction of poisonous metals and may be beneficial for different cell interactions (Schmuhl, Krieg, & Keizer, 2004).
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کلمات کلیدی:
Synthesis, characterization and modification of Gum Arabic microgels ... https://www.infona.pl/.../bwmeta1.element.elsevier-cf5854a9-c762-3420-9a1b-9f4e455... by M Farooq - 2017 - Cited by 2 - Related articles Gum Arabic (GA) microgels were successfully prepared via reverse micellization ... of Gum Arabic microgels for hemocompatibility and antimicrobial studies. Polymers | Free Full-Text | Activity and Mechanism of Antimicrobial ... www.mdpi.com/2073-4360/3/3/1512/htm by I Sovadinova - 2011 - Cited by 46 - Related articles Sep 13, 2011 - These results demonstrate that PMAs are a new antimicrobial platform with ... Polymer Nanogels and Microgels, Polymer-Inorganic Hybrids and Their .... More comprehensive studies of the PMAs biological activity are ..... In this report, we characterized the bactericidal action and hemocompatibility of PMAs ... Cytocompatibility evaluation of gum Arabic-coated ... - Future Medicine www.futuremedicine.com › Journal home › TOC by G Ciofani - 2014 - Cited by 17 - Related articles (2017) Synthesis, characterization and modification of Gum Arabic microgels for hemocompatibility and antimicrobial studies. Carbohydrate Polymers 156 ... mehtap sahiner - Google Akademik Alıntılar - Google Scholar scholar.google.com/citations?user=eG2b5kEAAAAJ&hl=tr p (AAm/TA)‐based IPN hydrogel films with antimicrobial and antioxidant properties ... of Gum Arabic microgels for hemocompatibility and antimicrobial studies. Cytocompatibility evaluation of gum Arabic-coated ultra-pure boron ... dx.doi.org › Journal home › TOC (2017) Synthesis, characterization and modification of Gum Arabic microgels for hemocompatibility and antimicrobial studies. Carbohydrate Polymers 156 ... Sparrho | Synthesis, characterization and modification of Gum Arabic https://www.sparrho.com/...microgels-for-hemocompatibility-and-antimicrobial-studie... Nov 16, 2016 - Gum Arabic (GA) microgels were successfully prepared via reverse ... of Gum Arabic microgels for hemocompatibility and antimicrobial studies. Turk M[au] - PubMed Result www.jrheum.org/external-ref?access_num=Turk%20M&link_type... ... Siddiq M, Turk M, Aktas N, Sahiner N. Synthesis, characterization and modification of Gum Arabic microgels for hemocompatibility and antimicrobial studies.
