دانلود رایگان مقاله لاتین میوژنز جنینی و بازسازی عضلات از سایت الزویر


عنوان فارسی مقاله:

تنظیم اپی ژنتیک میوژنز جنینی و بازسازی عضلات فرد بالغ با اصلاح متیلاسیون


عنوان انگلیسی مقاله:

The epigenetic regulation of embryonic myogenesis and adult muscle regeneration by histone methylation modification


سال انتشار : 2016



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مقدمه انگلیسی مقاله:

1. Introduction

Embryo myogenesis or adult muscle regeneration is the programming of a population of muscle progenitors, embryonic or fetal myoblasts and satellite cells (SCs) into committing to the myogenic lineages and of myoblasts into differentiating into mature myofibers. The formation of skeletal muscles involves both genetic and epigenetic changes that culminate in alterations in gene expression [1]. Chromatin-modifying enzymes and remodeling complexes orchestrate the pattern of gene expression and reprogram the myogenic lineage toward terminal differentiation [1,2]. The transcriptional regulation of muscle specification has been well characterized, and the role of histone acetylation modification in control of muscle-specific gene expression has been studied extensively, however, less is known about the role of histone methylation modification in this process [3]. Here, we review the potential roles of histone modifications during myogenesis with a focus on H3 lysine 27 tri-methylation (H3K27me3 ), H3 lysine 4 tri-methylation (H3K4me3 ) and H3 lysine 9 di/trimethylation (H3K9me2/3) markers at myogenic gene regulatory regions in myoblasts and satellite cells.



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کلمات کلیدی:

Concise Review: Epigenetic Regulation of Myogenesis in Health and ... https://www.ncbi.nlm.nih.gov › NCBI › Literature › PubMed Central (PMC) by MC Sincennes - ‎2016 - ‎Cited by 7 - ‎Related articles Jan 21, 2016 - Satellite cells are the adult muscle stem cells responsible for muscle regeneration ... Nearly half of the bivalent genes in embryonic stem cells are also marked by ... Epigenetic Regulation of Myogenic Transcription Factors. Epigenetic regulation of skeletal myogenesis. - NCBI https://www.ncbi.nlm.nih.gov/pubmed/20592865 by V Saccone - ‎2010 - ‎Cited by 41 - ‎Related articles Epigenetic regulation of skeletal myogenesis. ... stem cells, either by reprogramming embryonic stem cells or by inducing pluripotency in adult skeletal muscles. Epigenetic regulation of myogenesis - Taylor & Francis Online www.tandfonline.com/doi/pdf/10.4161/epi.4.8.10258 by E Perdiguero - ‎2009 - ‎Cited by 71 - ‎Related articles Jan 10, 2009 - dispensable for de novo myogenesis in the adult.4 This discovery illustrates that dis- tinct molecular players govern embryonic and postnatal ... The epigenetic regulation of embryonic myogenesis and adult muscle ... www.isi-dl.com/item/167727 The epigenetic regulation of embryonic myogenesis and adult muscle regeneration by histone methylation modification. sciencedirect.com ... پاد: The epigenetic regulation of embryonic myogenesis and adult ... pad.um.ac.ir/file/view/11769892 Translate this page عنوان: The epigenetic regulation of embryonic myogenesis and adult muscle regeneration by histone methylation modification; نویسنده (گان): Wei Jin; Jian Peng; ... Epigenetic control of adult skeletal muscle stem cell functions onlinelibrary.wiley.com/doi/10.1111/febs.13065/pdf Skeletal muscle regeneration in the adult (de novo myogenesis) depends on ... about the highly intricate layers of epigenetic regulation involved in satel- ... DNA methyltransferase; ES, embryonic stem; Ezh, enhancer of zeste homolog; HAT, ... Epigenetic control of adult skeletal muscle stem cell functions ... onlinelibrary.wiley.com/doi/10.1111/febs.13065/full by J Segalés - ‎2015 - ‎Cited by 22 - ‎Related articles Oct 21, 2014 - Regulation of myogenesis in the embryo has been reviewed recently [27]. We focus on the epigenetic signatures of adult muscle stem cells and ...