دانلود رایگان مقاله لاتین عصاره خیار تلخ از سایت الزویر


عنوان فارسی مقاله:

ارزیابی ضد باکتری و آنتی بیوفیلم عصاره میوه خیار تلخ پوشش داده شده نانوذرات نقره


عنوان انگلیسی مقاله:

Antibacterial and antibiofilm assessment of Momordica charantia fruit extract coated silver nanoparticle


سال انتشار : 2016



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مقدمه انگلیسی مقاله:

1. Introduction

The problem of multiple drug resistance in microbes is growing and the outlook for the use of antimicrobial drugs in the future is still uncertain. Therefore, considerable attention is needed to reduce this problem, for example, to minimize the use of antibiotics, develop research to better understand the genetic mechanisms of resistance, and to continue studies to develop new drugs that are cost effective and eco-friendly. Therefore, the ultimate goal is to offer appropriate and efficient antimicrobial drugs to the society. Currently, nanotechnology has gained importance in the fields of biology, chemistry, physics, and material sciences (Elumalai et al., 2010; Singh et al., 2009). Nanotechnology has made it possible to develop and fabricate different dimensioned nanoparticles (Marambio-Jones and Hoek, 2010). The nanomaterials can be synthesized by different methods including chemical, physical, irradiation, and biological methods. The chemical or physical methods of nanoparticle synthesis have resulted in environmental contaminations, since the chemical procedures involved in the synthesis of nanomaterials generate a large amount of hazardous products (Zhang et al., 2008). Thus, there is a need for clean, safe, ecofriendly, and environmentally non-toxic method of nanoparticle synthesis. The green synthesis of nanoparticle using plant parts such as bark, root, leaves, fruit, flowers, rhizoids, and latex show different dimensions including the size, shape, and dispersion which have more efficacy than those synthesized from the chemical and physical procedures. Therefore, the use of plants for nanoparticle synthesis has compatibility for pharmaceutical and other biomedical applications, as they do not involve toxic chemicals for the synthesis of nanoparticles (Vijayaraghavan and Nalini, 2010; Crooks et al., 2001). Among the several noble metal nanoparticles, silver nanoparticles (AgNPs) have attracted special attention due to their distinct properties, which include favorable electrical conductivity, chemical stability, catalytic and antibacterial activity (Sharma et al., 2009). Compared to larger AgNPs, smaller AgNPs have a greater binding surface and show more bactericidal activity (Kvitek et al., 2008). Their antimicrobial activities are attributed to the unique physico-chemical characteristics of AgNPs, such as the high surface area, mass ratio, high reactivity, and sizes in the nanometer range, which confer on them a major advantage for the development of alternative products against multi-drug resistant microorganisms (Martínez-Gutierrez et al., 2010). Momordica charantia is a tropical and subtropical vine of the family Cucurbitaceae, widely grown in Asia, Africa, and the Caribbean for its edible fruit, which is extremely bitter. The Latin name Momordica means “to bite,” referring to the jagged edges of the leaves, which appear as if they have been bitten. It has shown antibacterial, anticancerous, antileukemic, antiprotozoal, antitumorous, antiviral, antiparasitic, antifungal, anti-obesity, anti-ulcer, hypoglycemi and, immune stimulant activities (Alam et al., 2009; Gupta et al., 2010; Agrawal and Beohar, 2010; Santos et al., 2012). It has been used by natural health practitioners for diabetes, cancer, high cholesterol, viral infections and bacterial infections (Grover and Yadav, 2004; Beloin et al., 2005). The main constituents of M. charantia responsible for the medicinal properties are triterpenes, proteins, steroids, alkaloids and other phenolic compounds (Budrat and Shotipruk, 2008; Saeed et al., 2010). Based on these perspectives, the present study was undertaken to synthesize silver nanoparticle using the fruit extract of M. charantia. In addition, the antibacterial and antibiofilm activity of the synthesized silver nanoparticle was tested against Gram positive and Gram negative bacteria.



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کلمات کلیدی:

Antidiabetic Evaluation of Momordica charantia L Fruit Extracts https://www.ncbi.nlm.nih.gov › NCBI › Literature › PubMed Central (PMC) by S Tahira - ‎2014 - ‎Cited by 2 - ‎Related articles Mar 17, 2015 - To investigate hypoglycaemic, hypolipidaemic and pancreatic beta cell regeneration activities of Momordica charantia L fruits (MC). Antidiabetic effects of Momordica charantia (bitter melon) and its ... https://www.ncbi.nlm.nih.gov › NCBI › Literature › PubMed Central (PMC) by B Joseph - ‎2013 - ‎Cited by 100 - ‎Related articles The charantin from bitter melon fruit was extracted and estimated by high ..... Overall, the author covered most of the details pertaining to effect of blood glucose by ... Evaluation of hypoglycemic and hypolipidemic effects of ethanolic extracts of ... Antibacterial and antibiofilm assessment of Momordica charantia fruit ... https://www.infona.pl/.../bwmeta1.element.elsevier-fbd8b24b-ba20-340e-ac16-f91eaf5e... by B Malaikozhundan - ‎2016 - ‎Cited by 1 - ‎Related articles Silver nanoparticles were synthesized using the fruit extracts of Momordica ... assessment of Momordica charantia fruit extract coated silver nanoparticle. Anthelmintic activity of silver-extract nanoparticles synthesized from ... https://bmccomplementalternmed.biomedcentral.com/articles/10.../s12906-016-1219-5 by MMO Rashid - ‎2016 - ‎Related articles Jul 26, 2016 - After mixing silver nanoparticles and extracts, coating was given on nanoparticles using polyaniline. ... Momordica charantia L. (bitter melon) is one of the most important species ... of green synthesized silver nanoparticles using M. charantia fruit extract. .... Evaluation of Ag-Extract NPs through FTIR spectra. [PDF]Effects of Momordica charantia (Bitter Melon) on Ischemic Diabetic ... www.mdpi.com/1420-3049/22/3/488/pdf by A Czompa - ‎2017 Mar 20, 2017 - It is a popular food item in India and China, where its raw, bitter fruit, tender leaves and shoots are consumed as ... These studies were extended to assess its capacity to mitigate ... (B) Effect of bitter melon extract on serum glucose metabolism. ..... covered with mounting medium and glass slide covers. In Vitro Evaluation of Antioxidants of Fruit Extract of Momordica ... pubs.acs.org/doi/abs/10.1021/jf9025986 by R Kumar - ‎2010 - ‎Cited by 18 - ‎Related articles Jan 13, 2010 - The antioxidant activity of the total aqueous extract (TAE) and total phenolic extract (TPE) of Momordica charantia fruits was assayed by ...