دانلود رایگان مقاله لاتین سرامید سیتوتوکسیک از سایت الزویر
عنوان فارسی مقاله:
سرامید سیتوتوکسیک جدید از Heteroxenia ghardaqensis و اثر حفاظتی عصاره کلروفرم در برابر سمیت کادمیوم در موش
عنوان انگلیسی مقاله:
A new cytotoxic ceramide from Heteroxenia ghardaqensis and protective effect of chloroform extract against cadmium toxicity in rats
سال انتشار : 2016
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مقدمه انگلیسی مقاله:
1. Introduction
The Red Sea ecosystem represents one of the most promising areas as a source of medicinal and nutritional natural products (Elshamy et al., 2013). Soft corals (Octocorallia, Alcyonacea) contain not only diverse classes of secondary metabolites. The extracts of soft corals have various pharmacological activities such as antitumor, antibacterial, antiviral, antifungal, anti-inflammatory, antipyretic, hypoglycaemic and antioxidant (Edrada et al., 2000; Mohamed et al., 2012). The softcorals belonging to the genus Heteroxenia are rich in sesquiterpenoids, diterpenes, ceramides, acylglycerols and sterols (Elshamy et al., 2013; Edrada et al., 2000; Mohamed et al., 2012; Kashman et al., 1978). Cadmium (Cd2+) is a ubiquitous industrial and environmental pollutant that accumulates in humans. The tissues that accumulate Cd2+ include the kidneys, lungs, reproductive organs and nervous system. Cd2+ causes genotoxicity and cancer in some tissues and nonmalignant chronic toxicity in others. Cadmium accumulates in the adrenal gland after entering the body. The order of important organs that contain cadmium is adrenal gland > liver > kidney > hypothalamus > cerebral cortex, with the adrenal gland ranked as No. 1 (Mithal, 1981; Leal et al., 2007; Mukhtar et al., 2002). Continuing our work on H. ghardaqensis (Elshamy et al., 2013), and in our target for finding new leading bioactive materials from some Egyptian Red Sea marine organisms. The present study deals with the isolation and identification of cytotoxic ceramides and other secondary metabolites. Additionally, the protective role of CHCl3 extract against adrenal glands toxicity induced by cadmium in rats was evaluated.
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کلمات کلیدی:
A new cytotoxic ceramide from Heteroxenia ... - chemeurope.com www.chemeurope.com › Home › Publications Dec 14, 2014 - A new cytotoxic ceramide from Heteroxenia ghardaqensis and protective effect of chloroform extract against cadmium toxicity in rats. A new cytotoxic ceramide from Heteroxenia ghardaqensis and ... - خانه zoodyab.ir/.../122046-a-new-cytotoxic-ceramide-from-heteroxenia... Translate this page The ceramides (1) and (2) showed moderate cytotoxic activity as growth inhibitors of human hept-G2 cancer cell lines. The protective action of the chloroform ... A new cytotoxic ceramide from Heteroxenia ... - Chemie.de www.chemie.de › Fachpublikationen - Translate this page Dec 8, 2014 - A new cytotoxic ceramide from Heteroxenia ghardaqensis and protective effect of chloroform extract against cadmium toxicity in rats. Sparrho | A new cytotoxic ceramide from Heteroxenia ghardaqensis and https://www.sparrho.com/...cytotoxic-ceramide-from-heteroxenia.../9e483a/ A new cytotoxic ceramide from Heteroxenia ghardaqensis and protective effect of chloroform extract against cadmium toxicity in rats. Imported: 27 Oct '16 ... Bioactive Compounds and Extracts of Heteroxenia ghardaqensis, 978 ... www.morebooks.de/store/gb/book/bioactive...heteroxenia.../978-3-659-67793-9 Jan 20, 2015 - Bioactive Compounds and Extracts of Heteroxenia ghardaqensis, ... chemical constituents of the Egyptian Red sea soft coral, Heteroxenia ghardaqensis. ... Toxicity, cytotoxic, Steroids, Heteroxenia ghardaqensis, ceramides. Abdelsamed Elshamy - Google Scholar Citations scholar.google.gr/citations?user=Yx4b5f0AAAAJ&hl=en A new cytotoxic ceramide from Heteroxenia ghardaqensis and protective effect of chloroform extract against cadmium toxicity in rats. AF Abdel-Razik, MI Nassar, ... Novel Ceramides from the Fungus Lactarium volemus - Journal of ... pubs.acs.org/doi/abs/10.1021/np010088+ by JM Yue - 2001 - Cited by 18 - Related articles Aug 31, 2001 - A new cytotoxic ceramide from Heteroxenia ghardaqensis and protective effect of chloroform extract against cadmium toxicity in rats. Ayman F. [PDF]Soft coral Cespitularia stolonifera: New cytotoxic ceramides and ... cjnmcpu.com/tryw/homeAction!downloadArticleFile.action?attachType=PDF&id... Feb 20, 2017 - The extract and the two ceramides (1) and (1a) exhibited significant cytotoxic ...... cytotoxic ceramide from Heteroxenia ghardaqensis and.
