دانلود رایگان مقاله لاتین زوجین نابارور با و بدون عفونت تناسلی Chalmydia trachomatis از سایت الزویر
عنوان فارسی مقاله:
مطالعه مقایسه ای در زوجین نابارور با و بدون عفونت تناسلی Chalmydia trachomatis
عنوان انگلیسی مقاله:
Comparative study in infertile couples with and without Chlamydia trachomatis genital infection
سال انتشار : 2017
بخشی از مقاله انگلیسی:
Chlamydia trachomatis
(C. trachomatis), an intracellular bacterium, is the cause of the most frequently sexually transmitted disease (STD), resulting in about 100 million new cases annually worldwide [1]. Previous studies have reported that the prevalence of C. trachomatis ranged from 1.7% to 17% among European women [2] and from 1%-40% among asymptomatic men with a longstanding history of couple infertility [3], depending on the method of diagnosis, social background, area of residence, occupation, gender, and among others. Approximately 50% males and 80% females with Chlamydia show no symptoms in the early stage of infection, consequently, many of these individuals remain undiagnosed and are often poorly or inadequately treated [4]. Therefore, the true prevalence of this infection is not clear, and may remain unknown for several years or even longer. Standard microbiologic tests were commonly used to diagnosis C. trachomatis infections in the past, but studies have proved that this method may fail to reveal the pathogen, owing to high-proportion false negative results [5]. Thus, the DNA amplification method is increasingly universal. This method has a high sensitivity (99%) and specificity (100%), and has been accepted as the gold standard for the identification of C. trachomatis infections. [6, 7]. Since C. trachomatis is often asymptomatic and treatment is often delayed, the infection is often transmitted to sexual partner(s) [8]. It can cause fallopian tube salpingitis, cervicitis, and pelvic inflammatory disease (PID), which in turn can cause infertility and ectopic pregnancy in women with chronic infections [9]. Research has shown that microbiologic tests done on semen revealed a high proportion (43%) of C. trachomatis -specific DNA in semen from men with azoospermia [10], suggesting that hronic progression of C. trachomatis in the male genital tract may lead to urethritis, epididymitis, and even obstructive azoospermia [11]. Some subfertile couples are seeking ART treatment due to STD infection. Some studies report that the subfertile men with genitourinary infection caused by C. trachomatis had increased sperm DNA fragmentation [12], leading to sperm apoptosis [13] and low to sperm quality [10]. In animal experiments, C. trachomatis infection has been shown to inhibit oocyte transport in the mouse oviduct [14]. These studies suggest that C. trachomatis infection has the potential to negatively affect gamete formation and development. Despite the advances in knowledge about C. trachomatis infection, the impact of prior infection C. trachomatis on clinical outcomes after successful treatment is unknown. Therefore, the present study was carried out to evaluate C. trachomatis infection in subfertile couples I south China that were diagnosed by Taq-man PCR, and to deteremine whether the infection has any adverse effects on the clinical outcomes after treatment is completed.
کلمات کلیدی:
The impact of Chlamydia trachomatis infection on sperm parameters ... journals.sagepub.com/doi/abs/10.1177/0956462417735245 by M Moazenchi Oct 25, 2017 - The impact of Chlamydia trachomatis infection on sperm parameters and male fertility: A comprehensive study .... U. Male serum Chlamydia trachomatis IgA and IgG, but not heat shock protein 60 IgG, correlates with negatively affected semen characteristics and lower pregnancy rates in the infertile couple. [PDF]Tubal damage in infertile women: prediction using chlamydia serology citeseerx.ist.psu.edu/viewdoc/download;jsessionid...?doi=10.1.1.516.5451... without delay. Key words: chlamydia/infertility/pelvis/serology/tubal damage. Introduction. Couples may present to their family doctor complaining of infertility after .... This is the first report of its kind employing a large population of infertile women for comparative analysis. Our study using laparoscopy on all patients confirms ... Male Reproductive Dysfunction - Page 314 - Google Books Result https://books.google.com/books?isbn=9350252201 Basu SC - 2011 - Medical Reactive oxygen species influence the acrosome reaction but not acrosin activity in human spermatozoa. Int JAndrol 1999; 2:37-42. Comhaire F, Rowe PJ, Farley TM. The effect ofdoxy-cycline in infertile couples with male accessory gland infection: A double blind prospective study. Int JAndrol 1986; 9(2):91-8. Weidner W ...
