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عنوان فارسی مقاله:
بهبود خشکی دهان ناشی از تشعشع با طب سوزنی
عنوان انگلیسی مقاله:
Improvement of radiation-induced xerostomia with acupuncture: A retrospective analysis
سال انتشار : 2014
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مقدمه انگلیسی مقاله:
1. Introduction
Xerostomia is a well-known side effect in patients who have undergone radiotherapy with or without chemotherapy for head and neck cancer (HNC) [1]. Radiation-induced fibrosis and/or scarring of the salivary glands causes decreased salivary secretion [2]. Xerostomia may result in significant morbidity with impairments in speaking, eating, and swallowing, decreased sense of taste, and increased risk of dental caries [3,4]. Despite advancements of dosedelivering technologies such as intensity-modulated radiotherapy (IMRT) to protect a portion of parotid glands from high-dose radi- Research previously presented as a poster at the 2013 American Academy of Physical Medicine and Rehabilitation National Meeting in Washington, DC. ∗ Corresponding author at: 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA. Tel.: +1 414 805 7368; fax: +1 414 955 0104. E-mail addresses: hongwu@mcw.edu, wu 128@yahoo.com (H. Wu). ation, xerostomia continues to be common in patients with HNC after radiation [5–7]. IMRT’s use is also limited due to its increased expense, risk of marginal miss, and lack of universal availability [5,6]. Currently, xerostomia is often treated with saliva substitutes and/or cholinergic agonists, such as pilocarpine hydrochloride. These treatments are short acting requiring frequent dosing and in the case of pilocarpine the reported response rate is 31–54% [8]. In addition, HNC patients are often unable to tolerate longterm use of pilocarpine secondary to its associated side effects such as sweating, rhinitis, chills, nausea, urinary frequency, and cardiac arrhythmias [8,9]. Several studies have examined the use of acupuncture on cancer related symptoms including xerostomia with mixed results [10–12]. Furthermore, the techniques used in these studies vary in type of acupuncture, acupuncture points, and number of treatments performed. These studies frequently involved manual and/or auricular acupuncture without the use of electro acupuncture.
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