دانلود رایگان مقاله لاتین تولید رادیوایزوتوپ از سایت الزویر
عنوان فارسی مقاله:
تولید رادیوایزوتوپ علوم پزشکی با پرتو ذرات آلفا
عنوان انگلیسی مقاله:
Production of medical Sc radioisotopes with an alpha particle beam
سال انتشار : 2016
برای دانلود رایگان مقاله تولید رادیوایزوتوپ اینجا کلیک نمایید.
مقدمه انگلیسی مقاله:
1. Introduction
Recently, there has been steadily growing interest in the medical applications of Sc radioisotopes. The longer half-life of the scandium β+ emitters, 44 gSc and 43Sc (T1/2=3.97 h and T1/2=3.89 h, respectively), compared to that of other PET radioisotopes like 18F (T1/2=109.8 min), 68Ga (T1/2=67.7 min), 60Cu (T1/2=23.7 min), 11C (T1/2=20.3 min), 13N (T1/2=10.0 min), 15O (T1/2=122.2 s), potentially permits their regional distribution following production at a single central cyclotron facility. Other diagnostic radioisotopes that could be made at a central facility are 61Cu (T1/2=3.3 h), 64Cu (T1/2=12.7 h), 76Br (T1/2=16.2 h), 89Zr (T1/ 2=78.4 h) and 124I (T1/2=4.2 d) but, with the exception of 61Cu, all have a positron branch lower than 30%. Another advantage in the use of Sc as a diagnostic radioisotope lies in the other scandium radioisotope, i.e. 47Sc (T1/2=3.35 d) which is a promising low-energy β- emitter for targeted radiotherapy and therefore represents an ideal theranostic pair (Del Vecchio et al., 2007; Baum and Kulkarni, 2012; Verburg et al., 2014; Wright et al., 2015) for the β+ emitting 44Sc or 43Sc radioisotopes. The accelerator production routes using proton induced nuclear reactions for the formation of the Sc positron emitters were recently investigated in a number of papers (Krajewski et al., 2012, 2013; Severin et al., 2012; Müller et al., 2013, 2014; Hoehr et al., 2014; Hernandez et al., 2014; van der Meulen et al., 2015; Valdovinos et al., 2015) where natural and isotopically enriched Ca targets were discussed. Besides the “classic” Positron Emission Tomography (PET) application of 43Sc and 44Sc, the latter isotope has also been proposed as an ideal candidate for the new method of three photon PET (Mausner et al., 1998; Grignon et al., 2007; Müller et al., 2014; Thirlof et al., 2015), a method substantially improving the spatial resolution of PET techniques and allowing for patient dose reduction (Lang et al., 2013). Similarly, deuteron beams were recently used (Huclier-Markai et al., 2014; Alliot et al., 2015a, 2015b; Duchemin et al., 2015) for the production of the 44 m,gSc isomeric pair by the ARRONAX group. In this case the heavier mass of the projectile substantially increased the production efficiency of the high spin, longer lived isomeric state of 44Sc in comparison with the ground state production. In spite of the fact that some Sc β+ emitters were already produced by the E.O. Lawrence cyclotron in 1937 using an 11 MeV alpha-particle
برای دانلود رایگان مقاله تولید رادیوایزوتوپ اینجا کلیک نمایید.
کلمات کلیدی:
[PDF]Production of medical Sc radioisotopes with an alpha particle beam iranarze.ir/wp-content/uploads/2016/10/E271.pdf Jul 4, 2016 - Alpha particle beam. 43,44Sc radioisotopes. Radioisotope production in vivo 44 mSc /44 gSc generator. Thick Target Yield. A B S T R A C T. [PDF]Medical Radioisotopes Produced Using the Alpha Particle Beam from ... przyrbwn.icm.edu.pl/APP/PDF/127/a127z5p08.pdf Medical Radioisotopes Produced Using the Alpha Particle. Beam from the Warsaw Heavy Ion Cyclotron. K. Szkliniarzb, J. Jastrz¦bskia,*, A. Bilewiczc, ... Medical Radioisotopes Produced Using the Alpha Particle Beam from ... psjd.icm.edu.pl/.../bwmeta1.element.bwnjournal-article-appv127n5... - Translate this page by K Szkliniarz - 2015 - Cited by 3 - Related articles The internal alpha particle beam of the heavy ion cyclotron operated by the Heavy Ion Laboratory (HIL) of the University of Warsaw has a maximum energy of 32 ... Production of medical Sc radioisotopes with an alpha particle beam ... https://www.researchgate.net/.../304812925_Production_of_medical_Sc_radioisotopes_... The internal α-particle beam of the Warsaw Heavy Ion Cyclotron was used to produce research quantities of the medically interesting Sc radioisotopes from ... Medical Radioisotopes Produced Using the Alpha Particle Beam from ... https://www.researchgate.net/.../277930986_Medical_Radioisotopes_Produced_Using_t... Apr 4, 2017 - The internal alpha particle beam of the heavy ion cyclotron operated by the Heavy Ion Laboratory (HIL) of the University of Warsaw has a ... Medical Radioisotopes Produced Using the Alpha Particle Beam from ... search.ebscohost.com/login.aspx?direct=true&profile=ehost...site... by K SZKLINIARZ - 2015 - Cited by 3 - Related articles Title: Medical Radioisotopes Produced Using the Alpha Particle Beam from the Warsaw Heavy Ion Cyclotron. Language: English; Authors: SZKLINIARZ, K.1 Searches related to radioisotopes with an alpha particle beam alpha particle charge beta particle beta particle definition gamma particle beta particle charge mass of beta particle alpha particle definition alpha particle decay equation
