دانلود رایگان مقاله لاتین تشخیصی پوکی استخوان از سایت الزویر
عنوان فارسی مقاله:
دستگاه های تشخیصی برای پوکی استخوان در جمعیت عمومی: بررسی سیستماتیک
عنوان انگلیسی مقاله:
Diagnostic devices for osteoporosis in the general population: A systematic review
سال انتشار : 2016
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مقدمه انگلیسی مقاله:
1. Introduction
Osteoporosis is characterized by low bone mass and micro-architectural deterioration of bone tissue leading to increased risk of fractures [1]. One in three women and one in six men will suffer at least one osteoporotic fracture during their lifetime [2]. The disease is silent until the event of a fracture. Cross-sectional studies have consistently found that osteoporosis is under-diagnosed both in the general population [3] and in high-risk groups [4,5]. The diagnostic gap is further exaggerated by the fact that even in industrialized countries such as the US, examination rates for osteoporosis and prescription of pharmacological therapy for osteoporosis have been declining [6]. Even though Fracure Liasion Services are cost-effective and most likely also cost-saving [7], these coordinated services are lacking in many institutions. The current gold standard for diagnosing osteoporosis is dual photon X-ray absorptiometry (DXA), defined as bone mineral density (BMD) N2.5 standard deviations below the mean of young reference populations [8]. Fracture risk is inversely related to BMD [9], but as BMD is normally distributed, a much larger proportion of the population has osteopenic BMD values (i.e. in the range from −1 to −2.5 SD) rather than values in the osteoporotic range. Therefore, the majority of fractures occur in the osteopenic group despite a lower individual risk of fracture [10]. Furthermore, the elements of altered bone quality and individual risk of falling, both of which have substantial impact on the risk of fractures [11,12], are not captured by DXA, thus potentially reducing the predictive value of an examination. Finally, DXA is not universally available in all countries or healthcare systems. Therefore, the search for other tools capable of either differentiating patients at high risk of future osteoporotic fractures or alternatively identifying the same high risk groups as DXA by employing simpler, more accessible methods is ongoing and could help narrow the diagnostic gap in osteoporosis. Previously, we performed a systematic review of the fracture risk prediction of different algorithms based on clinical risk factors, finding that more complex algorithms did not perform better than simpler ones [13]. Recently, reviews of selected technical equipment designed to be used as an alternative or adjunct to DXA have been performed [14– 16]. Though interesting, most comparisons of technical devices against DXA have been performed in non-population based settings, or by combining population-based with non population-based studies. This poses a problem as diagnostic performance is critically dependent on the disease prevalence in the evaluated population. Furthermore, different populations have been used as reference populations amongst manufactures of the same equipment, leading to differences in reported standard deviations [17]. This has further added to the confusion and made the search for a common diagnostic T-score cutoff an act of futility. Finally, the correlation between methodologies cannot be assumed to be independent of artifacts such as osteoarthrosis that may have an uneven influence between devices and between measurement sites. Thus, the utility of technical devices for population-based screening for osteoporosis has not been thoroughly addressed.
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کلمات کلیدی:
Diagnostic devices for osteoporosis in the general population: A ... www.sciencedirect.com/science/article/pii/S8756328216302307 by MP Høiberg - 2016 - Cited by 5 - Related articles Cross-sectional studies have consistently found that osteoporosis is under-diagnosed both in the general population [3] and in high-risk groups [4] and [5]. Prevalence and features of osteoporosis in the French general ... www.sciencedirect.com/science/article/pii/S1297319X09000062 by É Lespessailles - 2009 - Cited by 49 - Related articles There is currently little data available concerning the rates of diagnosis and treatment of osteoporosis in the general population in France which can be used as ... Facts and Statistics | International Osteoporosis Foundation https://www.iofbonehealth.org/facts-statistics Facts and statistics about osteoporosis around the world, risks and prevention ... Men account for 25% of hip fractures occurring in the over 50 population (24). Osteoporosis - Wikipedia https://en.wikipedia.org/wiki/Osteoporosis Osteoporosis is a disease where increased bone weakness increases the risk of a broken bone .... In general, immobilization causes bone loss (following the 'use it or lose it' rule). ..... Data from the United States shows a decrease in osteoporosis within the general population and in white women, from 18% in 1994 to 10% in ... FRAX®: Prediction of Major Osteoporotic Fractures in Women from the ... journals.plos.org/plosone/article?id=10.1371/journal.pone.0083436 by K Briot - 2013 - Cited by 13 - Related articles Dec 30, 2013 - The population for this study consisted of 1748 women (mean age 74.2 ... major osteoporotic and vertebral fractures in the general population. Diagnostic devices for osteoporosis in the general population https://www.researchgate.net/.../306271273_Diagnostic_devices_for_osteoporosis_in_th... Nov 11, 2016 - References, authors & citations for 'Diagnostic devices for osteoporosis in the general population: A systematic review' on ResearchGate. Public priorities for osteoporosis and fracture research: results from a ... link.springer.com/article/10.1007/s11657-017-0340-5 by Z Paskins - 2017 Apr 28, 2017 - Public priorities for osteoporosis and fracture research: results from a general population survey. Authors; Authors and affiliations. Prevalence of osteoporosis and vitamin D receptor gene polymor ... mjiri.iums.ac.ir/browse.php?a_id=3024&sid=1&slc_lang=en by Z Mohammadi - 2015 - Cited by 2 - Related articles Prevalence of osteoporosis and vitamin D receptor gene polymor-phisms (FokI) in an Iranian general population based study (Kurdistan) (IMOS).
