دانلود رایگان مقاله لاتین تراکم ناپذیری آترواسکلروز عروق کرونر از سایت الزویر
عنوان فارسی مقاله:
تحقیق تجربی سلامت و تراکم ناپذیری آترواسکلروز عروق کرونر از طریق ارتباط تصویر دیجیتال
عنوان انگلیسی مقاله:
Experimental verification of the healthy and atherosclerotic coronary arteries incompressibility via Digital Image Correlation
سال انتشار : 2016
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مقدمه انگلیسی مقاله:
1. Introduction
Cardiovascular disease is a wide range of clinical disorders responsible for a high rate of deaths throughout the world.1 Atherosclerosis is ranked as the most hazardous shapes of the cardiovascular disease causes by dehydrated food, smoking, pollution, stress, etc., which can alter the elastin and collagen content of the arterial wall (microstructure) and, consequently, the mechanical properties of the arterial wall.2e4 Atherosclerotic plaque is also enabled to block the blood occlusion in the arteries and, as a result, invokes a significant variation not only in the hemodynamics of the blood flow but also the mechanical properties of the arterial wall.5e7 So far there are many studies have been measured the mechanical properties of the arterial wall using different mechanical approaches, such as linear,8 nonlinear isotropic9 and anisotropic10 solid mechanics via constitutive equations.11 However, the arterial tissue can be considered as an incompressible material which is in common among almost many of the studies have been conducted so far. However, up to now there is no agreement with this assumption and, therefore, there is a need to set an experimental study to confirm that. In the past, most studies considered the arterial wall as an isotropic elastic material. In characterizing the linear mechanical properties of the arterial walls several researchers have employed the postulation of arterial walls’ incompressibility.12,13 Although this assumption may significantly abridge the mechanical behavior of the arterial wall, this would provide a more simplified mechanical behavior of the arterial wall with fewer constants, such as elastic modulus as well as Poisson’s ratio. In addition, so far there is no experimental evidence to prove the incompressibility of the human coronary arterial wall. Lawton et al.14 showed that the aortic strips were behaved like an incompressible material under different stretch ranges. The canine carotid arteries were also found to be incompressible through an internal pressurization test.15 It is well known that an impeccably incompressible material under a hydrostatic stress tolerates no comparative alteration in distance among material elements. Although it would be difficult to consider a soft tissue as an incompressible material, because all materials display some degree of compressibility. However, in some especial conditions the behavior of these materials under strains can be approximated as an incompressible material. It is known that a nearly incompressible material would not show a considerable deformation and, as a result, would have the Poisson’s ratio of 0.5. That is, the value of the axial/longitudinal strain must be nearly two times of the transverse strain. Hasegawa et al.16 proposed a noninvasive ultrasound technique to experimentally measure the Poisson’s ratio of the carotid artery and abdominal aorta. Their method employed a high spatial resolution technique to measure the both in axial and radial directions of the arterial wall and their results finally reported the value of 0.46 as the Poisson’s ratio of the arterial wall. Carew et al.17 subjected a group of 11 thoracic aorta segments of the dogs to a series of internal pressure and their results reported the Poisson’s ratio of closely to 0.5. Thereafter, the longitudinal and circumferential strain of the tissues due to internal pressure were measured accurately to prove the incompressibility (Poisson’s ratio of 0.5) of the arterial wall.18,19 To this end, most studies measured the elastic modulus, computed the hyperelastic parameters, or analyzed the nonlinear anisotropic response of the arterial tissues Therefore, there is not much result on the Poisson’s ratio of these tissue under various strain rates, namely 5 and 20 mm/min. In addition, those studies measured the Poisson’s ratio mostly have been performed on the animal models. Therefore, this study was designed to explore the Poisson’s ratio of the healthy and atherosclerotic human coronary arteries via Digital Image Correlation (DIC) technique under the strain rates of 5 and 20 mm/min. The results would provide a verification for the current assumption employed by many studies on the Poisson’s ratio of the coronary arterial walls not only in the healthy but also in the diseased condition.
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کلمات کلیدی:
A COMBINATION OF EXPERIMENTAL AND NUMERICAL ANALYSES ... www.worldscientific.com › ... › Available Issues › Volume 27, Issue 04 by A Karimi - 2015 - Cited by 7 - Related articles Jun 19, 2015 - Therefore, this study aimed to perform an experimental study to evaluate ... (2016) Experimental verification of the healthy and atherosclerotic ... A combination of experimental and numerical methods to investigate ... www.tandfonline.com/doi/abs/10.1080/21655979.2016.1212134 by A Karimi - 2017 - Cited by 2 - Related articles Few studies so far have been conducted to calculate the isotropic or anisotropic mechanical properties of the healthy and atherosclerotic human coronary ... Experimental Gingivitis Induces Systemic Inflammatory Markers in ... journals.plos.org/plosone/article?id=10.1371/journal.pone.0055265 by J Eberhard - 2013 - Cited by 25 - Related articles Feb 7, 2013 - Experimentally induced gingivitis in young, healthy volunteers was initiated by termination .... As safety parameter and as marker of pre-existing atherosclerosis, the intima-media ... Verification of Bacterial Plaque Composition. Atherosclerosis: New Insights for the Healthcare Professional: 2013 ... https://books.google.com/books?isbn=1481650823 2013 - Medical Harbin Medical University: Differentiated miRNA expression and validation of signaling ... from 10 Apolipoprotein E (apoE) knockout mice (apoE-/) and 10 healthy C57BL/6 (B6) mice. ... Experimental & Molecular Medicine, 2013;45():e 13. Diabetes and Cardiovascular Disease https://books.google.com/books?isbn=1592599087 Michael T. Johnstone, Aristidis Veves - 2007 - Medical Experimental verification of these potential mechanisms of atherogenesis ... “Ideal” animal models of insulin resistance or diabetes and atherosclerosis should have ... fasting and postprandial insulin levels and relatively normal glucose levels. Atherosclerosis Disease Management https://books.google.com/books?isbn=1441972226 Jasjit S. Suri, Chirinjeev Kathuria, Filippo Molinari - 2010 - Medical Cheng C, Tempel D, van Haperen R et al (2006) Atherosclerotic lesion size and vulnerability are determined ... Hemodynamics of the normal human carotid bifurcation – in vitro and in vivo studies. ... Performance and experimental-verification. Exercise and the Heart in Health and Disease, Second Edition, https://books.google.com/books?isbn=1420002864 Shepherd, Miller - 1998 - Medical Experimental Verification Any hypothesis must ultimately be verified experimentally. We have ... Further, there are no good animal models of atherosclerosis.
