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عنوان فارسی مقاله:
بررسی همودینامیک تاثیر ترومبوز داخل مجرا بر فشار دیوار در مدل آنوریسم آئورت استنت سه لایه تحت جریان ضربانی
عنوان انگلیسی مقاله:
Hemodynamic investigation of intraluminal thrombus effect on the wall stress in a stented three-layered aortic aneurysm model under pulsatile flow
سال انتشار : 2015
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مقدمه انگلیسی مقاله:
1. Introduction
Aneurysm is an irreversible bulge in weak parts of an artery which its occurrences in the abdominal aortic is more common than other parts of the vascular system. Abdominal Aortic Aneurysm (AAA) is a focal, balloon-like dilation of the terminal aortic segment that occurs gradually over a span of years.1,2 This condition is growing in commonness in the aged people, with approximately 150,000 new cases being diagnosed every year.3,4 These aneurysms tend to enlarge over years but rupture abruptly when wall stress exceeds wall strength. These injuries are common in the aging population and, consequently, are increasingly responsible for morbidity and mortality.5e9 Although the pathogenesis is still not well understood, there is an abundance of biological, clinical, histopathological, and mechanical data on AAAs, and there has been considerable improvement in the biomechanical modeling of these lesions.10 Excessive expansion of aneurysm eventually leads to its rupture, which is the thirteenth cause of mortality in the United States alone.11 The traditional treatments for this problem include open surgery, cutting the damaged artery and its replacement with polyester graft. However, minimally invasive technique such as endovascular stent graft has been substituted nowadays.12 Di Martino et al.13 investigated a real three-dimensional abdominal aortic aneurysm and their results provided a quantitative local evaluation of the stresses due to local structural and fluid dynamic conditions. The structural and fluid dynamic conditions for aortic aneurysm were investigated by Liber et al.14 They also considered thrombus and the interaction between thrombus and fluid and also investigated the in- fluence of the stent filament size on the intra aneurysmal flow dynamics in a sidewall aneurysm model in vitro. Their result showed that the stenting procedure would signifi- cantly reduce the intra-aneurysmal vorticity and the mean circulation inside the aneurysm diminished reduced to less than 3% of its value before stenting.15
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کلمات کلیدی:
STUDY OF PLAQUE VULNERABILITY IN CORONARY ARTERY ... www.worldscientific.com › ... › Available Issues › Volume 26, Issue 01 by A Karimi - 2014 - Cited by 56 - Related articles Feb 26, 2014 - (2015) Hemodynamic investigation of intraluminal thrombus effect on the wall stress in a stented three-layered aortic aneurysm model under ... A computational fluid–structure interaction model ... - Bioscience Reports www.bioscirep.org/content/ppbioscirep/36/6/e00431.full.pdf by A Khosravi - 2016 - Related articles In the present study, three layers of the ascending aorta in respect to the time and space at various blood pressures .... mechanical behaviour was investigated in FE software. ..... intraluminal thrombus effect on the wall stress in a stented. A computational fluid–structure interaction model of the blood flow in ... journals.sagepub.com/doi/abs/10.1177/1708538115594095 by R Razaghi - 2016 - Cited by 12 - Related articles In this study, a three-dimensional (3D) computational fluid–structure ... R. A finite element study of balloon expandable stent for plaque and arterial wall ... R. Plaque and arterial vulnerability investigation in a three-layer atherosclerotic ... Hemodynamic investigation of intraluminal thrombus effect on the wall stress in a ... Numerical investigation of the haemodynamics in the human fetal ... pubmedcentralcanada.ca/pmcc/articles/PMC5041159/pdf/bsr036e384.pdf by T Rezaee - 2016 - Related articles [11] investigated DV shunting in growth-restricted fetuses and the effect of umbilical .... A single shell layer with a thickness value of 0.5 mm was used globally. .... Modelling blood flow in umbilical vein and ductus venosus. Figure 3. 3D model and its ..... intraluminal thrombus effect on the wall stress in a stented three-layered ...