دانلود رایگان مقاله لاتین انعقاد گلبول قرمز از سایت الزویر
عنوان فارسی مقاله:
انعقاد گلبول قرمز ناشی از درمان پلاسما در دمای پایین
عنوان انگلیسی مقاله:
Red blood cell coagulation induced by low-temperature plasma treatment
سال انتشار : 2016
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مقدمه انگلیسی مقاله:
1. Introduction
Blood circulation carries components including erythrocytes, which transport O2 and collect CO2; leukocytes, which detect invasion of foreign bodies; thrombocytes, which are responsible for clot formation to stop bleeding; and plasma, which acts as a solvent. Loss of large amounts of these components is life-threatening because of the lack of a central machinery to maintain body homeostasis. Hence, many kinds of technology to achieve hemostasis have been developed and improved. For example, to control surgical site bleeding, numerous clinical and technical advances have been established to control spurting and oozing by clipping and ligation, and using surgical hemostats and energy devices,respectively [1e6]. Notably, the energy devices and surgical hemostats [7] have been used for oozing to obtain greater visibility rather than to prevent excessive blood loss by spurting. Their performances have been improved to further minimize their invasiveness in order to reduce the risk of intraoperative and postoperative complications [8]. Use of high-frequency electrical coagulators (HFECs), which cauterizes tissues by using electrical current flowing through stromal tissues to stop bleeding, can cause postoperative complications [8]. The basic mechanism of hemostasis in other energy devices is tissue coagulation, which is the same as that in HFECs. However, the basic mechanism of hemostasis by surgical hemostats is to maintain both platelet aggregation and activation of coagulation cascades that are targets for anti-coagulation therapy [9]. From the viewpoint of minimal invasiveness, the use of surgical hemostats has recently increased in order to decrease the use of HFECs in preventing postoperative complications by reducing the incidence of tissue coagulation [7]. Low-temperature plasma (LTP) at atmospheric pressure is available for use to control oozing bleeding by increasing blood coagulation activity and to prevent postoperative complications due to decreased tissue coagulation [10,11]. LTP treatment for hemostasis is generally assumed to be achieving by blood coagulation, like generation of clot formation by using the same mechanism as that in surgical hemostats for stimulating both platelets to aggregate and coagulation factors [12e14]. We recently demonstrated the plasma-induced aggregation of serum proteins, such as albumin and immunoglobulins [10], to generate membrane-like structures [10]. This suggested that LTP utilized much more abundant serum proteins (more than 70% of the total proteins) than coagulation factors (approximately 10% of the total proteins) for blood clot formation. Thus, our findings indicate the possibility that LTP treatment has the potential to induce whole-blood clot formation by mechanisms with or without platelet aggregation and coagulation factors. In this study, we aimed to evaluate the effectiveness of LTP treatment involving erythrocytes to form clots based on the fact that plasma technology can convert red blood cells (RBCs), which make up approximately 35e50% of the blood volume [15], into an ingredient for blood coagulation. Erythrocytes isolated by using density gradient were suspended in phosphate-buffered saline (PBS) and subjected to a series of experiments for LTP treatments using two plasma devices; one is developed by Nagoya Univ. and the others by our institute and Nikon [10]. Data from histological and electron microscopic analyses of plasma-treated RBCs revealed that clot formation and hemolysis are essential processes for clot formation by LTP treatment.
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کلمات کلیدی:
Red Blood Cell Coagulation Induced by Low ... - ResearchGate https://www.researchgate.net/.../299476124_Red_Blood_Cell_Coagulation_Induced_by... Oct 16, 2016 - Low-temperature plasma (LTP) treatment promotes blood clot formation by stimulation of the both platelet aggregation and coagulation factors. [PDF]The effects of red blood cells on coagulation: a thromboelastographic ... www.anesth-pain-med.org/journal/download_pdf.php?spage=133&volume=4... Key Words: coagulation, red blood cell, thromboelastography. INTRODUCTION ..... adenosine diphosphate-induced aggregation of human platelets in tube flow. Procoagulant and proinflammatory effects of red blood cells on ... onlinelibrary.wiley.com/doi/10.1111/jth.13041/full by B Østerud - 2015 - Cited by 4 - Related articles Jul 27, 2015 - Neutrophils and/or platelets are not required for RBC-induced potentiation .... reports on RBC-DARC and its effect on TF-triggered coagulation. Procoagulant and proinflammatory effects of red ... - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/jth.13041/pdf by B Østerud - 2015 - Cited by 4 - Related articles expression of TF in monocytes, red blood cells (RBCs) are understudied. ... triggered activation of coagulation induced by LPS. Thus, we explored the effect of ... Fibrinogen, red blood cells, and factor XIII in venous thrombosis onlinelibrary.wiley.com/doi/10.1111/jth.12918/pdf by BL Walton - 2015 - Cited by 7 - Related articles red blood cell and fibrin content; however, the pathophys- iologic mechanisms that ... During coagulation, thrombin cleaves N-terminal peptides from the Aa- and ..... fibrinogen in patients with venous thrombosis are not caused by acute phase ... The adaptability of red blood cells | Cardiovascular Diabetology | Full ... https://cardiab.biomedcentral.com/articles/10.1186/1475-2840-12-63 by E Pretorius - 2013 - Cited by 20 - Related articles Apr 11, 2013 - Red blood cells Iron Glucose Diabetes Hemochromatosis Scanning electron ... They also play a fundamental role in the coagulation system and in ... of glucose to healthy whole blood will induce changes to these cells, and ... Identification of signalling cascades involved in red blood cell ... www.bioscirep.org/content/35/2/e00187 by EB Kostova - 2015 - Cited by 4 - Related articles Apr 1, 2015 - As a calcium ionophore, ionomycin induces calcium influx in RBC, ..... including NO scavenging [9–11] and promotion of coagulation [6–8]. Erythrocyte fragility - Wikipedia https://en.wikipedia.org/wiki/Erythrocyte_fragility Erythrocyte fragility refers to the propensity of erythrocytes (red blood cells, RBC) to hemolyse ... stability refers to cells' resistance to both stress-induced lysis and spontaneous auto-lysis. .... coagulation · Bleeding time; animal enzyme.
