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عنوان فارسی مقاله:
اثرات اندازه، توزیع و کنتراست ضریب نرم کانونی آئورت با خصوصیات سیلیکونی در ترویج موج نبض
عنوان انگلیسی مقاله:
In silico characterization of the effects of size, distribution, and modulus contrast of aortic focal softening on pulse wave propagations
سال انتشار : 2015
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مقدمه انگلیسی مقاله:
1. Introduction
A Dell Precision with Intel Core i7-3840QM and 32 GB Ram was used to perform dynamic two-way Fluid Structure Interaction (FSI) simulations of pulse wave propagations along the walls of a 3D aortic geometry. The Coupled Eulerian-Lagrangian (CEL) explicit solver of Abaqus 6.11e1 (Simulia, RI, USA) was used to describe the fluid dynamics and to capture the fluidesolid interactions. Defining the initial position of a moving particle in the material at the reference time, the new position of the same particle at the current time and the resulted velocity and acceleration can be obtained either in Lagrangian coordinate system (e.g. such as for the motion of the wall material), or the Eulerian coordinate system (e.g. such as for the motion of the fluid material), and based on the principle of coordinate-invariance, the displacement, velocity and acceleration fields obtained from either coordinate system are equal. In the CEL solver for the finite element method, the motions of the particles in fluid (i.e. flow) are formulated in Eulerian coordinate system, in which the mesh topology consists of elements that are affixed in the space while material is allowed to cross in/out of the element boundaries. However, the motions for the solid (i.e. aortic wall) domains are formulated using Lagrangian coordinate system, where the elements are affixed to and move with the particles during the material deformation. In the present model, the Lagrangian part was constructed as a straight cylindrical geometry (L Z 250 mm; di Z 24 mm; h Z 2.2 mm), with a Young’s modulus of Ew Z 5.12 MPa, density of rw Z 1050 kg/m3 , and Poisson’s ratio of nw Z 0.48.37e39 The Eulerian domain was established to encompass the entire Lagrangian domain in order to accommodate the potential presence of fluid and the FSI thereof on the deformed geometries at all times during the simulation. Without the loss of generality in generating relevant wave dynamics, fluid was assumed to be Newtonian, with material properties as density rf Z 1000 kg/m3 , reference sound speed cf Z 1483 m/s and viscosity hf Z 0.0001 N/m2 . 40,41 Boundary conditions on the inlet and outlet were applied as full constraint in all 6 degrees of freedom. A pulse profile with magnitude V0 Z 5 m/s was applied as the inlet flow, acting as the drive in generating the FSI-induced pulsatile motions in the wall. The pulse profile is a smooth step function over time. The flow parameters were chosen in consistency with similar numerical and experimental studies,30,31,35,36 primarily in order to induce strong enough displacement in the aortic walls, so the resulted wave propagations would be fully detectable.
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کلمات کلیدی:
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