دانلود رایگان مقاله لاتین ارزیابی پلاسمای آسیل کارتنین از سایت الزویر
عنوان فارسی مقاله:
ارزیابی پلاسمای آسیل کارتنین قبل و بعد از کاهش وزن در افراد چاق
عنوان انگلیسی مقاله:
Assessment of plasma acylcarnitines before and after weight loss in obese subjects
سال انتشار : 2016
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مقدمه انگلیسی مقاله:
1. Introduction
With the increased incidence of obesity and type 2 diabetes mellitus, many studies focus on the interaction between lipid and glucose metabolism, and the relationship to insulin resistance. Within the concept of lipotoxicity increased lipid levels are proposed to interfere with insulin signalling, eventually leading to hyperglycemia. However, the exact mechanisms and the individual lipids that induce insulin resistance have not been characterised definitively. From a cellular point of view, lipotoxicity is thought to occur on a cytosolic level via lipid overload (e.g. ceramides, gangliosides or diacylglycerol) [1e4]. Reduced mitochondrial content or capacity may result in elevated intracellular lipids [3,5]. Alternatively, increased fatty acid oxidation (FAO) rates that are not followed by increased tricarboxylic acid cycle (TCA) activity have been proposed to induce insulin resistance via accumulation of different mitochondrial metabolites such as acylcarnitines [1,6,7].
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کلمات کلیدی:
ACRN - Clinical: Acylcarnitines, Quantitative, Plasma www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/82413 ACRN : Acylcarnitine analysis enables the diagnosis of many disorders of ... for Elevations of C8, C6, and C10 Acylcarnitines (also applies to any plasma C8, C6 ... Genetics in Medicine - Acylcarnitine profile analysis - Nature www.nature.com › Journal home › Archive › ACMG Standards and Guidelines A comprehensive metabolic evaluation typically also includes the analysis of plasma amino acids, urine organic acids, and plasma carnitine (free and total). Vademecum Metabolicum: Diagnosis and Treatment of Inborn Errors of ... https://books.google.com/books?isbn=3794528166 Johannes Zschocke, Georg Friedrich Hoffmann - 2011 Acylcarnitines plasma, OA urine Elevated C 4 DD: SCAD deficiency (page 94), ... in several countries): outpatient assessment, continue breast feeding Confirm. Plasma Acylcarnitines Are Associated With Physical Performance in ... biomedgerontology.oxfordjournals.org/content/66A/5/548.full by H Lum - 2011 - Cited by 17 - Related articles Mar 2, 2011 - Acylcarnitine factor scores were inversely related to physical performance ..... Thus, profiling of plasma acylcarnitines affords an assessment of ... Laboratory Tests for the Assessment of Nutritional Status, Second ... https://books.google.com/books?isbn=0849385067 Howerde E. Sauberlich - 1999 - Medical Roe, D. S., Terada, N., and Willington, D. S., Automated analysis for free and short-chain acylcarnitine in plasma with a centrifugal analyzer, Clin. Chem, 38,2215 ... Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 ... onlinelibrary.wiley.com/doi/10.1038/oby.2009.510/full by SJ Mihalik - 2010 - Cited by 195 - Related articles Plasma long-chain AcylCN species are increased in obesity and T2DM, ... The AcylCN analysis in newborn screening has resulted in the identification of several ... A Handbook for the Assessment of Children's Behaviours https://books.google.com/books?isbn=1119978424 Jonathan O. H. Williams, Peter D. Hill - 2012 - Medical Look for elevated plasma lactate; cerebellar atrophy; CoQ10 in muscle (not plasma). ... Also test pyruvate, ketone bodies, plasma acylcarnitines, urinary organic ... Searches related to Assessment of plasma acylcarnitines acylcarnitine test what is acylcarnitine acylcarnitine deficiency acylcarnitine definition acylcarnitine wiki acylcarnitine profile newborn screening low acylcarnitine levels acylcarnitine function
